Medicine

Advancing ASO therapies from growth to execution

.Competing enthusiasms.R.S., M.S., H.G. and A.A.R. are coordinators of the 1M1M campaign. H.G. as well as A.A.R. are board of supervisors participants and R.S., M.S. and also A.A.R. are participants of the scientific consultatory board of N1C. A.A.R. reveals job by LUMC, which has licenses on exon-skipping technology, some of which has actually been actually licensed to BioMarin and ultimately sublicensed to Sarepta. As co-inventor of some of these patents, A.A.R. was allowed to a share of royalties. A.A.R. even further makes known acting as ad hoc professional for PTC Therapies, Sarepta Therapies, Regenxbio, Dyne Therapeutics, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco as well as Astra Zeneca. Previously 5 years, A.A.R. also conducted impromptu consulting for Alpha Anomeric. A.A.R. likewise mentions registration of the medical boards of advisers of Eisai, Hybridize Rehabs, Silence Therapies, Sarepta Therapies, Sapreme and Mitorx. Before 5 years, A.A.R. was additionally a clinical advisory board participant for ProQR. Pay for A.A.R. u00e2 s consulting and also advising activities is actually paid out to LUMC. Previously 5 years, LUMC additionally got speaker honoraria from PTC Rehabs, Alnylam Netherlands, Italfarmaco as well as Pfizer as well as moneying for deal analysis coming from Sapreme, Eisai, Galapagos, Synaffix and Alpha Anomeric. Venture funding is actually gotten from Sarepta Therapeutics and also Entrada by means of unrestricted gives. H.G. possesses nothing to divulge in regard to the subjects covered in this particular document. In the past 5 years, he has actually also obtained working as a consultant honoraria coming from UCB. M.S. obtained working as a consultant gratuity from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly and Solaxa previously 5 years, all unconnected to the present document. R.S. has nothing to reveal in connection with the subject matters dealt with within this composition. She has obtained speaker and/or working as a consultant honoraria or even financing additions from Abbvie, Bial, STADA as well as Everpharma previously 5 years.

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